Leads India

PIlot Fermentor

PIlot Fermentor

Our Pilot Fermentors enhance your bioprocess development by providing the bridge between lab work and the large scale in the real world. We are the Pilot fermentors major manufacturers in Chennai and we offer quality and dependable fermentors that are designed either to be used in research, industry, or even in the educational field.
High Flexible Small bench top system suitable for research And Industry for both Microbial and cell culture application
  • Ideal system for trouble free operation
  • Well equipped for batch , fed batch & continuous
  • Minimal Foot print
  • Up gradation for multiple system
  • Flexible control system for customized function
  • Open end OPC server – integrate with other device
  • Biojenik SCADA user friendly mimics
  • Complete Data Management
  • Compliance 21 CFR part 11
  • Suitable for both microbial/cell culture
  • Multiple feeding/gas lines
  • All ports and plugs stand for international std
  • Sampling either from bottom or top or both

Servo motors ensure minimum and max. speed Without affecting the torque

Features That Ensure Process Excellence

● Scalable Design: The one suited to the scale-up of lab-scale fermentation to pilot-scale production.

● Precise Control Systems: Control pH, temperature, dissolved oxygen and agitation to ensure consistency in the results.

● Automated Monitoring: Automated data recording of the vital process parameters.

● Strong and Small: Rugged design can be utilized in pilot labs with compact space-saving construction.

Applications Across Industries

● Biopharmaceuticals: Pilot-scale manufacturing of vaccines, enzymes and therapeutic proteins.
● Biotechnology research and development: Strains optimization and process development research.
● Food and Beverage: Fermentation of Pilot fermentation of probiotics, dairy, and yeast-based products.
● Research on the environment: Research into biodegradation and into the treatment of wastewater.

Why Choose Our Pilot Fermentors?
Our fermenters have been designed to be reliable, scalable and efficient. A unit is against the international standards to be able to achieve reproducible results and long-term capability to operate. Your pilot-scale processes are made smooth and precise with user-friendly interfaces and a high level of automation.
Collaborate with reliable Pilot Fermentor manufacturers in Chennai in order to expand your research effectively, increase the reproducibility of the experimental results, and guarantee quality outcomes of the research for both industry and academic purposes.
Vessel
  • Vessel: Insitu- sterilizable single glass vessel , SS vessel ( on request) Top and bottom with SS LID with necessary ports and plugs
  • Volume: Total volume: 2.4 and 3.5 (3.1 on request)
  • Drive assemble: 4x baffles attached with top lid or around the vessel wall SS 316L
  • Bottom Driven : Direct drive Single Mechanical Seal Servo/DC motor Speed: 25 to 3000 rpm
  • Top Driven: Direct drive Single Mechanical seal Servo/DC motor Speed 25 to 3000 rpm
  • Air Bubble mixing: shear free mixing achieved by air bubbles instead of mechanical Agitator
  • Impeller: Marine Type for Axial flow mixing ( on request) Pitch Blade for Axial flow mixing ( on request) Rushton type for radial flow mixing . 6 blade x 2nos
  • Heating/cooling :             Electrical heating finger x 800 Watts 1 no. Or 400 Watts x 2nos Control for both Sterilization and culture temperature Cooling finger suit for water circulation with on/off Electrical Pulsed valve. Safety hood in SS.
  • Aeration:  Straight Tube: Submerged aeration for efficient dispersion bubbles Ring Sparger: submerged aeration for superior dispersion bubbles Sintered Sparger: submerged fine efficient low gas flow Filter: Cartridge Ceramic tube and Sintered SS with SS housing (0.2μ)
  • Gas Supply Module :Single gas line 2 Gas Mixing station 4 Gas mixing station 4 Gas mixing and 2 Gas overlay
  • Gas control:  Four Gas combined with 1x MFC Individual gas with MFC Individual gas with pulsed valv
  • Gas line accessories: Gas pressure control valve, Check valve, Pressure gauge, Flowmeters Hypodermic needle, sterile needle (Replace the hypodermic needle)
  • Gas ranges : Air: 2 vvm O2: 0.5 vvm N2: 1vvm CO2: 0.1vvm Various ranges can be selected (as per process requirement)
  • Gas Exhaust : Absolute filter (99.9999%) cartridge with SS housing with back pressure Control valve (Manual or Auto) Gas Condenser: water cooled condenser
  • Feed system4 x Fixed speed pump, 1 x Variable speed pump Additional Pump up to 6 Fixed speed, 1 x Variable speed ( on request) Sterile Cap with bottle: 250ml, 500ml 1000ml bottle with SS cap or PP cap With vent filter Height adjustable Dip tube immersed at the liquid bottom for Harvest /sampling
  • Rotor filter :  Cell retention filter ( pore size 20μm onwards) fixed with shaft itself.
  • Sampling/harvest : Dip tube with pinch cock assembly. (by Positive vessel pressure) Hypodermic needle septum collection from bottom Push back valve at the bottom
Control Module
  • Speed controller                       Direct Digital control system, Measurement and control cascaded with DO
    Controller. HMI via JENIK SCADA
    18.
  • Temperature controller     Suitable for both SIP and process temperature by activate the
    Cooling/ heating valve. Operate by JENIK SCADA
    Measurement : 0 to 150 Degree C 19.
  • PH controller                   Sterilizable Gel type PH probe, activate the Acid, base dosing pump
    Operation via JENIK SCADA Measuring range: 2 to 12PH
    20.
  • DO controller            Poloragraphic or Optical sensor enable to activate the final element
    Pulsed valve or MFC . Cascade with Gas mixing station, Agitator and
    Back pressure control valve. Measurment: 0 to 100%
    Control via JENIK SCADA
  • Antifoam/level                   Conduct type height adjustable probe activate antifoam correction
    Agent pump. For level activate the feed addition or harvest pump
    Control via JENIK SCADA
    22.
  • Redox/RH                           Sterilizable ORP probe controller activate the dosing pump or valve
    Measurment range: + 400 to -400mV Control via JENIK SCADA
    23.
  • Optical Density               Sterilizable Turbidity measurement probe activate dosing pump or valve
    Measurement: 0 to 250g/L . Control via
  • JENIK SCADA
    24. JENIK SCADA Software with process controller functions
    Customized operator interface, Display all process and set point
    values. Profile, cascade and manual operation
    Alarm and event for all parameters and deviation
    Different Access level, Recording and analyzing,
    Online recording all the set Point and measurement value,
    trend and text data Data can be exported to excel sheet
    Recording and analyzing, Online recording all the set point
    and measurement value, trend and text data Data can be exported to
    excel sheet
    One System is capable to operate up to 8 Fermenter
    25.
  • Hardware                            Suitable PC or Laptop with inbuilt OS –windows with run time
    License with std. system configuration suitable to operate the
    Software ( JENIK SCADA)
Accessories
  • Exit Gas Analyzer                           O2 measurement ( 0 to 25%) Co2 Measurement (0 to10%)
    Suitable to connect upto 4 fermenter. Suitable I/O connect
    with JENIK SCADA for data logging
  • Load cell                             Platform type weighing measurement of the liquid bottle or
    Fermenter. Accuracy ± 0.01g. Operate via JENIK SCADA
    Cascade operation with dosing pump
  • Ports and Needle                     12mm std ports, 12mm Needle.( 3mm and 4.5mm)
  • Impellers                           Rushton, Marine, Pitch blade ( 40mm,48mm and 60mm )
    Six blade, Four blade and two blade.
  • Light Hood                                    SS hood with LED , adjustable Intensity 0 to 100% from SCADA
  • Chiller                                 Suitable to operate one fermenter ( 800W) with 20 Lts tank
    Heat Load Delta T 10 Degree C
    Available the capacity to operate up to 8 Fermenter
  • Compressor                                10LPM @ 2bar with storage tank 25Lts including pressure regulator Pressure gauge, Moisture trap. Available higher capacity : to operate up to 8 fermenter